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Taxotere is a treatment popularly used to treat cancer
that is discovered or recurs after previous chemotherapy.
It is part of a group of medicines called taxanes, which
derive from the bark or pin needles of certain types of
yew trees. Unlike most chemotherapies Taxotere does not
stop cancer by interfering with its DNA or RNA. Instead
Taxotere interferes with the cell's microtubules. Microtubules
are cells' skeleton and help the movement of organelles
and chromosomes during division. By attacking the microtubules
Taxotere stops cancer cells from successfully dividing.
In worldwide phase II clinical trials, Taxotere demonstrated
the highest tumor response rates ever reported for a single
agent in this subject population. It is administered intravenously
for a variety of cancers. It is mostly used after a cancer
returns after platinum based chemotherapy.
Possible side effects to Taxotere include: nausea, vomiting,
fatigue, reduction of production of blood cells (1. lowers
the patient's immunity and therefore increases the chances
of infection and 2. reduces the number of platelets and
decreases the blood's ability to clot), skin rash, fluid
retention, hypersensitivity, hair loss, and diarrhea.
Before starting Taxotere treatment patients should discuss
its effects on fertility and their ability to conceive after
treatment. Also vaccinations should not be taken during
treatment which causes patients to be immuno-compromised.
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